Description

[7As,(+)]-6,7,7A,8-Tetrahydro-7-Methyl-5H-Benzo[G]-1,3-Benzodioxolo[6,5,4-De]Quinoline-11-Ol is a complex, optically active alkaloid derivative with a unique fused heterocyclic structure. This compound is valued as a critical advanced pharmaceutical intermediate and a versatile scaffold for research in medicinal chemistry. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing novel therapeutic agents and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential central nervous system (CNS) active compounds and other specialized pharmaceuticals.
• Medicinal Chemistry Research: Used as a core scaffold for designing and synthesizing new chemical entities (NCEs) for biological screening and drug discovery programs.
• Biochemical Tool Compound: Employed in pharmacological studies to investigate receptor interactions and enzyme inhibition due to its complex alkaloid-like structure.
• Asymmetric Synthesis: Utilized in stereoselective synthesis processes where its specific chiral configuration is crucial for creating enantiomerically pure final products.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	[7As,(+)]-6,7,7A,8-Tetrahydro-7-Methyl-5H-Benzo[G]-1,3-Benzodioxolo[6,5,4-De]Quinoline-11-Ol
CAS No.	3466-56-6
Molecular Formula	C19H19NO3
Molecular Weight	309.36 g/mol
Synonyms	(+)-Nuciferoline; (7aS)-6,7,7a,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-11-ol; (7aS)-7-Methyl-6,7,7a,8-tetrahydro-5H-[1,3]dioxolo[6,5,4-de]benzo[g]quinolin-11-ol; Nuciferoline; L-Nuciferoline; (7aS)-Nuciferoline; 1,3-Benzodioxolo(6,5,4-de)benzo(g)quinolin-11-ol, 6,7,7a,8-tetrahydro-7-methyl-, (7aS)-
EINECS	Contact for details

Quality Control

We supply [7As,(+)]-6,7,7A,8-Tetrahydro-7-Methyl-5H-Benzo[G]-1,3-Benzodioxolo[6,5,4-De]Quinoline-11-Ol in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results from advanced analytical techniques. Specifications can be developed to meet the requirements of cGMP and other stringent regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.