Description

9α-Hydroxy-9-Hydro-16-Dehydro-12-Methoxyibogamine-18-Carboxylic Acid Methyl Ester is a complex, semi-synthetic ibogaine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analytical study of novel therapeutic agents targeting neurological pathways. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in neuropharmacology and the development of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel ibogaine analogs and related therapeutic compounds.
• Reference Standard: Used in analytical chemistry for method development, validation, and quality control (HPLC, LC-MS) of related substances.
• Neurological Research: Employed in preclinical studies to investigate structure-activity relationships (SAR) and mechanisms of action affecting the central nervous system.
• Process Chemistry Development: Serves as a model compound for optimizing synthetic routes, scaling up production, and impurity profiling.
• Metabolite Studies: Utilized as an analytical standard for the identification and quantification of metabolic products in pharmacological research.

Basic Information

Product Name	9α-Hydroxy-9-Hydro-16-Dehydro-12-Methoxyibogamine-18-Carboxylic Acid Methyl Ester
CAS No.	3464-63-9
Molecular Formula	C₂₁H₂₆N₂O₄
Molecular Weight	370.45 g/mol
Synonyms	12-Methoxyibogamine-18-carboxylic acid, 9α-hydroxy-9,10-dihydro-16,17-didehydro-, methyl ester; Methyl 9α-hydroxy-9,10-dihydro-16,17-didehydro-12-methoxyibogamine-18-carboxylate; 9α-Hydroxy-9,10-dihydro-16,17-didehydro-12-methoxyibogamine-18-carboxylic acid methyl ester; 12-Methoxyibogamine-18-carboxylic acid methyl ester derivative; Ibogaine derivative 3464-63-9; 9α-Hydroxy-9-hydro-16-dehydro-12-methoxyibogamine-18-methyl ester
EINECS	Contact for details

Quality Control

Our 9α-Hydroxy-9-Hydro-16-Dehydro-12-Methoxyibogamine-18-Carboxylic Acid Methyl Ester is produced under controlled conditions to ensure high purity and batch-to-batch consistency suitable for research applications. All materials undergo rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR). A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	97.0% - 102.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.