Description

3-o-Methyl 17α-Estradiol is a synthetic, steroidal estrogen derivative, a key intermediate in the synthesis of more complex pharmaceutical compounds. Its value lies in its specific chemical structure, which allows for targeted research and development in endocrinology and hormone-related therapies. This high-purity intermediate is essential for pharmaceutical R&D laboratories, academic research institutions, and manufacturers specializing in steroid-based active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of advanced steroidal drugs and novel therapeutic agents.
• Endocrinology Research: Used as a reference standard or experimental compound in studies investigating estrogen receptor binding, metabolism, and biological activity.
• Hormone Analog Development: Serves as a precursor for creating modified estrogen analogs with tailored pharmacokinetic or pharmacodynamic profiles.
• Biochemical Research: Employed in academic and industrial labs to study steroidogenic pathways and enzyme interactions.
• API Manufacturing: Integrated into Good Manufacturing Practice (GMP) processes for the production of steroidal active pharmaceutical ingredients.
• Reference Standard: Utilized in analytical method development and validation for quality control in pharmaceutical production.

Basic Information

Item	Details
Product Name	3-o-Methyl 17α-Estradiol
CAS No.	3434-76-2
Molecular Formula	C19H26O2
Molecular Weight	286.41 g/mol
Synonyms	3-Methoxyestra-1,3,5(10)-triene-17β-ol; 3-Methoxy-17β-estradiol; 17β-Estradiol 3-methyl ether; 3-Methoxyestra-1,3,5(10)-trien-17β-ol; 3-ME2; 3-O-Methylestradiol
EINECS	Contact for details

Quality Control

Our 3-o-Methyl 17α-Estradiol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.