Description

5-Nitrogramine is a specialized nitro-substituted gramine derivative, a key synthetic intermediate in advanced organic synthesis. Its value lies in providing a reactive nitro group on the indole scaffold, enabling the construction of complex molecules for research and development. This compound is primarily required by the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel indole-based drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new plant growth regulators or pesticides that leverage the biological activity of the indole structure.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other specialty chemicals where the nitro-gramine moiety imparts specific functional properties.
• Biochemical Research: Employed as a probe or substrate in enzymatic studies and metabolic pathway investigations due to its specific structural features.
• Material Science: Potential use in the synthesis of organic electronic materials or advanced polymers requiring functionalized heterocyclic components.

Basic Information

Product Name	5-Nitrogramine
CAS No.	3414-64-0
Molecular Formula	C11H11N3O2
Molecular Weight	217.23 g/mol
Synonyms	5-Nitrogramine; 1-(5-Nitro-1H-indol-3-yl)-N,N-dimethylmethanamine; 3-(Dimethylaminomethyl)-5-nitroindole; 5-Nitro-3-(dimethylaminomethyl)indole; Gramine, 5-nitro-; 5-Nitrogramin; 5-Nitro-1H-indole-3-methanamine, N,N-dimethyl-
EINECS	Contact for details

Quality Control

Our 5-Nitrogramine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support its use in regulated research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.