Description

Z-Ala-Osu is a high-purity, protected amino acid derivative widely used as a key building block in peptide synthesis. Its primary value lies in its role as an activated ester, facilitating efficient and selective amide bond formation under mild conditions, which is critical for producing complex peptides with high fidelity. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors engaged in the development of therapeutic peptides, peptide hormones, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial reagent for the controlled, stepwise assembly of peptide chains on resin supports.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions to create peptides and peptide conjugates in solution.
• Pharmaceutical Intermediate: Serves as a key raw material in the synthesis of active pharmaceutical ingredients (APIs) for peptide-based drugs.
• Bioconjugation: Facilitates the labeling and modification of proteins, antibodies, and other biomolecules with alanine or peptide tags.
• Research & Development: Employed in academic and industrial R&D for exploring new peptide structures and their biological activities.
• Production of Protected Dipeptides: Acts as a starting material for generating more complex, custom-protected peptide fragments.

Basic Information

Product Name	Z-Ala-Osu
CAS No.	3401-36-3
Molecular Formula	C14H16N2O6
Molecular Weight	308.29 g/mol
Synonyms	N-Carbobenzoxy-L-alanine N-hydroxysuccinimide ester; Z-L-Ala-OSu; Cbz-L-Alanine N-succinimidyl ester; Nα-Cbz-L-alanine N-hydroxysuccinimide ester; N-(Benzyloxycarbonyl)-L-alanine succinimidyl ester; NSC 334381; (S)-2-(((Benzyloxy)carbonyl)amino)propanoic acid 2,5-dioxopyrrolidin-1-yl ester
EINECS	Contact for details

Quality Control

Our Z-Ala-Osu is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive quality assurance, with each lot accompanied by a detailed Certificate of Analysis (COA) verifying key parameters such as assay, enantiomeric purity, and impurity profiles. Our quality standards are designed to meet the rigorous demands of pharmaceutical research and GMP-grade production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	-15.0° to -18.0° (c=1 in DMF)
Melting Point	118°C - 122°C
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.