Description

Oleic Acid, [1-14C] is a carbon-14 radiolabeled analog of the common monounsaturated fatty acid, oleic acid. This compound is essential for advanced metabolic and biochemical research, enabling precise tracking of fatty acid uptake, distribution, and catabolism in biological systems. It is a critical tool for researchers in pharmaceutical development, lipid metabolism studies, and nutritional science who require high-specific-activity tracers for sensitive detection.

Application

• Metabolic Pathway Tracing: Used in in vitro and in vivo studies to elucidate the β-oxidation and incorporation pathways of oleic acid.
• Drug Discovery & Development: Serves as a tracer in ADME (Absorption, Distribution, Metabolism, and Excretion) studies for lipid-based therapeutics.
• Biochemical Research: Facilitates the study of lipid droplet formation, membrane lipid turnover, and signaling lipid biosynthesis.
• Nutritional Science: Enables precise investigation of dietary fat absorption, storage, and mobilization in model organisms.
• Enzyme Assays: Acts as a labeled substrate for assays involving lipases, desaturases, and acyl-CoA synthetases.

Basic Information

Product Name	Oleic Acid, [1-14C]
CAS No.	3343-81-5
Molecular Formula	C₁₈H₃₄O₂ (with 14C at the C-1 position)
Molecular Weight	~282.5 g/mol (varies with specific activity)
Synonyms	(9Z)-Octadec-9-enoic-1-14C acid; cis-9-Octadecenoic-1-14C acid; 14C-Oleic Acid; Radiolabeled Oleic Acid; [1-14C]Oleic Acid; 9-cis-Octadecenoic-1-14C acid; 18:1(n-9) fatty acid-1-14C
EINECS	Contact for details

Quality Control

Every batch of Oleic Acid, [1-14C] is manufactured and analyzed to meet the stringent requirements of research applications. Quality is assured through rigorous testing for radiochemical purity, chemical purity, and specific activity using techniques such as HPLC with radiometric detection. A comprehensive Certificate of Analysis (COA), detailing batch-specific data including radionuclidic purity and analytical chromatograms, is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C in the original solvent as supplied. This product is easily oxidized (store under inert atmosphere). For long-term storage, keep the container sealed under an inert atmosphere in a dedicated freezer. Users must follow all applicable radiation safety regulations for handling and storage.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Identification (HPLC, TLC)	Conforms to standard
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Concentration	0.1 mCi/mL in ethanol (or as specified)
Solvent	Ethanol, Toluene, or custom

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.