Description

3-Methylcholanthrene-4,5-Dihydrodiol is a high-purity, synthetic dihydrodiol derivative of the polycyclic aromatic hydrocarbon 3-methylcholanthrene. This compound is of significant value as a key biochemical intermediate and reference standard in advanced research applications. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, toxicology, and environmental analysis sectors for metabolic and carcinogenicity studies.

Application

• Biochemical Research: Used as a critical intermediate in studying the metabolic activation pathways of polycyclic aromatic hydrocarbons (PAHs).
• Toxicology Studies: Serves as a reference standard in in vitro and in vivo assays to investigate carcinogenic mechanisms and DNA adduct formation.
• Analytical Standard: Employed as a high-purity calibrant in chromatographic methods (HPLC, GC-MS) for the quantification of PAH metabolites.
• Enzymology: Utilized as a substrate for studies involving cytochrome P450 and epoxide hydrolase enzymes to understand bioactivation processes.
• Pharmaceutical Development: Acts as a tool compound in early-stage drug discovery programs targeting metabolic diseases and cancer.
• Environmental Analysis: Applied in method development for detecting and monitoring PAH derivatives and their biotransformation products in complex matrices.

Basic Information

Product Name	3-Methylcholanthrene-4,5-Dihydrodiol
CAS No.	3343-04-2
Molecular Formula	C21H18O2
Molecular Weight	302.37 g/mol
Synonyms	3-Methylcholanthrene-4,5-dihydrodiol; 3-MC-4,5-dihydrodiol; 4,5-Dihydro-3-methylcholanthrene-4,5-diol; 3-Methylcholanthrene trans-4,5-dihydrodiol; 1,2,3,10b-Tetrahydro-3-methylbenzo[j]acephenanthrylene-4,5-diol; trans-3-Methylcholanthrene-4,5-dihydrodiol; 3-MC-4,5-diol
EINECS	Contact for details

Quality Control

Our 3-Methylcholanthrene-4,5-Dihydrodiol is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.