Description

Ac-Gly-Onp is a specialized N-protected amino acid derivative, specifically the p-nitrophenyl ester of N-acetylglycine. This compound serves as a crucial activated ester intermediate in peptide synthesis and other organic coupling reactions, enabling efficient amide bond formation under mild conditions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the development of novel peptides, peptidomimetics, and other bioactive molecules.

Application

• Key building block in solid-phase and solution-phase peptide synthesis.
• Activated intermediate for the acylation of amines in medicinal chemistry research.
• Preparation of modified amino acids and peptide conjugates for biochemical studies.
• Use in the synthesis of custom peptides for drug discovery and development pipelines.
• Intermediate for creating linkers and spacers in bioconjugation and probe development.
• Research chemical for studying enzyme kinetics and protease activity.

Basic Information

Product Name	Ac-Gly-Onp
CAS No.	3304-61-8
Molecular Formula	C10H10N2O5
Molecular Weight	238.20 g/mol
Synonyms	N-Acetylglycine 4-Nitrophenyl Ester; N-Acetylglycine p-Nitrophenyl Ester; p-Nitrophenyl N-Acetylglycinate; Ac-Gly-ONp; Acetyl-glycine-ONp ester; 4-Nitrophenyl 2-acetamidoacetate; 2-Acetamidoacetic Acid 4-Nitrophenyl Ester
EINECS	Contact for details

Quality Control

Our Ac-Gly-Onp is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high purity for research and synthesis applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.