Description

6-Thioxanthine 5'-Monophosphate is a modified nucleotide monophosphate derivative of xanthine, featuring a sulfur substitution at the 6-position. This compound is a key intermediate and research chemical in the development of novel nucleoside analogs and enzyme inhibitors. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors. Its unique structure makes it valuable for probing biochemical pathways and synthesizing potential therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a crucial building block for the synthesis of novel purine nucleoside analogs with potential antiviral, anticancer, or anti-inflammatory activity.
• Biochemical Studies: Used as a substrate or inhibitor in enzymatic assays to study the function of kinases, phosphatases, and other nucleotide-processing enzymes.
• Probe Development: Acts as a precursor for labeled compounds (e.g., fluorescent or radioactive tags) used in molecular biology and diagnostic assay development.
• Antisense Oligonucleotide Synthesis: Can be incorporated into oligonucleotide sequences to modify their stability, binding affinity, or therapeutic properties.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and research laboratories for method development and validation.

Basic Information

Product Name	6-Thioxanthine 5'-Monophosphate
CAS No.	3237-49-8
Molecular Formula	C10H11N4O7PS
Molecular Weight	362.26 g/mol
Synonyms	6-Mercaptoxanthine 5'-Monophosphate; 6-Thioxanthosine 5'-Monophosphate; 6-Thioxanthylic Acid; Xanthine-6-thiol 5'-Monophosphate; 6-SH-XMP; 6-Thio-XMP; 9H-Purine-6-thiol, 2-amino-1,7-dihydro- (9CI); 6-Thioxanthine ribonucleotide
EINECS	Contact for details

Quality Control

Our 6-Thioxanthine 5'-Monophosphate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the product label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.