Description

1-Palmitoyl-2-Oleoyl-Sn-Glycerol is a high-purity, well-defined diacylglycerol (DAG) with the CAS number 3123-73-7. This structured lipid is a critical intermediate and reference standard for advanced research and product development in life sciences. It is essential for scientists and manufacturers in the pharmaceutical, nutraceutical, and specialty chemical industries who require precise molecular tools for lipid metabolism studies, formulation development, and the synthesis of complex bioactive compounds.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of phospholipids, prodrugs, and other lipid-based drug delivery systems (e.g., liposomes, solid lipid nanoparticles).
• Biochemical & Nutritional Studies: Used as a substrate or standard in enzymatic assays to study lipase activity, lipid digestion, and absorption pathways.
• Reference Standard: Serves as a high-purity calibrant in analytical methods (HPLC, GC, MS) for the quantification of diacylglycerols in complex biological matrices.
• Cosmetic & Personal Care Formulations: Employed as a skin-compatible emollient and structuring agent in high-end skincare products.
• Synthetic Chemistry: A versatile building block for the regioselective synthesis of more complex triglycerides, glycolipids, and other structured lipids.

Basic Information

Product Name	1-Palmitoyl-2-Oleoyl-sn-Glycerol
CAS No.	3123-73-7
Molecular Formula	C37H72O5
Molecular Weight	596.98 g/mol
Synonyms	1-Palmitoyl-2-oleoyl-rac-glycerol; 1-Palmitoyl-2-oleoyl-glycerol; POPG; 1,2-Diacyl-sn-glycerol (C16:0, C18:1); DG(16:0/18:1); Diolein Palmitate; Glycerol 1-palmitate 2-oleate; sn-1-Palmitoyl-2-oleoylglycerol; (2R)-2,3-Dihydroxypropyl (9Z)-octadec-9-enoate hexadecanoate
EINECS	221-496-6

Quality Control

Our 1-Palmitoyl-2-Oleoyl-sn-Glycerol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays (HPLC, GC) and identity confirmation (IR, MS), to ensure it meets the high standards required for research and industrial applications. A detailed Certificate of Analysis (COA) with lot-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white waxy solid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
1-Palmitoyl-2-Oleoyl Isomer Content	≥ 95.0% (of total DAG)
Acid Value	≤ 1.0 mg KOH/g
Peroxide Value	≤ 5.0 meq/kg
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.