Description

Gdp-D-Mannose CAS NO 3123-67-9 is a high-purity, activated sugar nucleotide derivative, specifically guanosine diphosphate mannose, which serves as a critical biochemical precursor for mannosylation reactions. This compound is essential for research and production in glycobiology, enabling the study and synthesis of complex carbohydrates and glycoconjugates. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies developing advanced therapeutics, diagnostics, and enzymatic processes.

Application

• Glycobiology Research: Essential substrate for studying glycosyltransferase enzymes and biosynthetic pathways of glycoproteins and glycolipids.
• Enzymatic Synthesis: Used as a mannose donor in the in vitro enzymatic synthesis of oligosaccharides, glycopeptides, and other complex glycostructures.
• Pharmaceutical Development: Critical raw material in the research and production of carbohydrate-based vaccines, antibody-drug conjugates (ADCs), and other biopharmaceuticals.
• Diagnostic Reagents: Employed in the manufacture of diagnostic kits and assays that detect specific glycosylation patterns associated with diseases.
• Biocatalyst & Enzyme Studies: Serves as a cofactor or substrate in assays to characterize enzyme kinetics, specificity, and inhibition.
• Metabolic Pathway Analysis: Used in tracing and understanding metabolic fluxes in nucleotide sugar metabolism within cells.

Basic Information

Product Name	Gdp-D-Mannose
CAS No.	3123-67-9
Molecular Formula	C16H25N5O16P2
Molecular Weight	605.34 g/mol
Synonyms	GDP-D-Mannose; Guanosine 5'-(trihydrogen diphosphate), P'-α-D-mannopyranosyl ester; Guanosine diphosphate mannose; GDP-α-D-mannose; GDP-Man; GDPM; 5'-O-[(α-D-Mannopyranosyloxy)hydroxyphosphinyl]guanosine; EINECS 221-513-6
EINECS	221-513-6

Quality Control

Our Gdp-D-Mannose is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and bioprocessing. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality guidelines and can supply material tailored to specific project requirements, including research-grade and higher purity tiers.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95% (Anhydrous basis)
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Biological Activity	Contact for details
Endotoxin	< 10 EU/mg (if required)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.