Description

Adenosine-5'-Carboxaldehyde is a high-purity biochemical building block and a key intermediate in nucleoside chemistry. This compound is essential for the synthesis of modified nucleosides and nucleotides, which are critical for pharmaceutical research and diagnostic applications. It is primarily utilized by researchers and manufacturers in the life sciences sector, including pharmaceutical development, biotechnology, and academic research, for creating novel therapeutic agents and molecular probes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel adenosine receptor agonists/antagonists and other nucleoside-based therapeutics.
• Bioconjugation & Probe Synthesis: Used to create labeled nucleosides for diagnostic assays, imaging probes, and bioconjugation applications due to its reactive aldehyde group.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and the development of enzyme inhibitors.
• Nucleotide Analog Development: Key starting material for the preparation of carbocyclic and acyclic nucleotide analogs with potential antiviral or anticancer activity.
• Biochemical Tool Compound: Employed in enzymatic studies and as a standard in analytical method development for nucleoside analysis.

Basic Information

Product Name	Adenosine-5'-Carboxaldehyde
CAS No.	3110-98-3
Molecular Formula	C11H13N5O4
Molecular Weight	279.25 g/mol
Synonyms	5'-Aldehydeadenosine; 5'-Deoxy-5'-oxoadenosine; 9-β-D-Ribofuranosyl-9H-purin-6-amine-5'-carboxaldehyde; Adenosine 5'-aldehyde; 5'-Formyladenosine; Adenosine, 5'-deoxy-5'-oxo-; 5'-Carboxaldehydeadenosine
EINECS	221-474-7

Quality Control

Our Adenosine-5'-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.