Description

Doxifluridine CAS NO 3094-09-5 is a fluorinated pyrimidine nucleoside analog with significant pharmacological activity. This compound is a key intermediate and active pharmaceutical ingredient (API) in the development of targeted cancer therapeutics. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in oncology drug development and clinical studies. Our supply ensures high purity and consistent quality, which are critical for reliable research outcomes and manufacturing processes.

Application

• Oncology Drug Development: Serves as a critical active pharmaceutical ingredient (API) in the formulation of anti-cancer medications.
• Pharmaceutical Intermediates: Used as a high-purity building block in the synthesis of more complex fluoropyrimidine-based therapeutics.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate mechanisms of action, metabolism, and efficacy of fluoropyrimidines.
• Preclinical Studies: Essential for pharmacokinetic, pharmacodynamic, and toxicology assessments in animal models.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.
• Antimetabolite Research: A tool compound for studying cell proliferation inhibition and DNA/RNA synthesis interference in various cancer cell lines.

Basic Information

Product Name	Doxifluridine
CAS No.	3094-09-5
Molecular Formula	C9H11FN2O5
Molecular Weight	246.19 g/mol
Synonyms	5'-Deoxy-5-fluorouridine; 5-DFUR; Ro 21-9738; Furtulon; 5-Fluoro-5'-deoxyuridine; 1-[(2R,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione
EINECS	221-444-7

Quality Control

Our Doxifluridine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.