Description

Methyl Chenodeoxycholate is a methylated derivative of the primary bile acid chenodeoxycholic acid. This compound serves as a crucial intermediate and reference standard in pharmaceutical research and development, particularly for liver and metabolic studies. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity biochemical tools for drug discovery and metabolic pathway analysis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel therapeutic agents targeting liver and metabolic diseases.
• Biochemical Research: Used as a reference standard and reagent in studies of bile acid metabolism, liver function, and cholestasis.
• Cell Culture & In Vitro Studies: Employed in laboratory settings to investigate the biological effects of bile acids on cell membranes and signaling pathways.
• Analytical Standard: Serves as a high-purity calibration standard for analytical methods such as HPLC and LC-MS in quality control and bioanalytical laboratories.
• Metabolite Synthesis: Utilized in the preparation of specific metabolites for pharmacokinetic and toxicological profiling.

Basic Information

Product Name	Methyl Chenodeoxycholate
CAS No.	3057-04-3
Molecular Formula	C25H42O4
Molecular Weight	406.60 g/mol
Synonyms	Methyl 3α,7α-dihydroxy-5β-cholan-24-oate; Chenodeoxycholic Acid Methyl Ester; 3α,7α-Dihydroxy-5β-cholan-24-oic Acid Methyl Ester; Methyl 3α,7α-dihydroxy-5β-cholanoate; Methylchenodeoxycholate; CDCA Methyl Ester
EINECS	221-292-5

Quality Control

Our Methyl Chenodeoxycholate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.