Description

n-Formylnornicotine is a key intermediate and reference standard in the synthesis and analytical study of nicotine and related alkaloids. Its importance lies in its role as a precursor for the development of novel nicotine analogs and as a critical tool for metabolic and pharmacokinetic research. This compound is primarily needed by research institutions, pharmaceutical developers, and analytical laboratories focused on tobacco science, neuropharmacology, and substance analysis.

Application

• Pharmaceutical Research Intermediate: Serves as a crucial building block in the synthesis of new nicotine derivatives and potential therapeutic agents targeting nicotinic acetylcholine receptors.
• Analytical Reference Standard: Used as a high-purity standard in HPLC, GC-MS, and LC-MS methods for the quantification and qualification of nicotine and its metabolites in various matrices.
• Metabolic Pathway Studies: Employed in research to investigate the biotransformation and metabolic pathways of nicotine and related compounds in biological systems.
• Biochemical Tool Compound: Utilized in in vitro assays to study receptor binding affinity, enzyme inhibition, and other biochemical interactions related to nicotinic signaling.
• Forensic Analysis: Acts as a reference material in forensic toxicology for the accurate identification and measurement of nicotine analogs.
• Chemical Synthesis: Functions as a specialized intermediate in organic synthesis for creating labeled compounds or structurally modified alkaloids for research purposes.

Basic Information

Item	Detail
Product Name	n-Formylnornicotine
CAS No.	3000-81-5
Molecular Formula	C11H14N2O
Molecular Weight	190.24 g/mol
Synonyms	1-Methyl-5-(3-pyridyl)-2-pyrrolidinone; 5-(3-Pyridyl)-1-methyl-2-pyrrolidinone; N-Formylnornicotine; Norcotinine; Nornicotine Formamide; 1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one; 3-(1-Methyl-2-oxopyrrolidin-5-yl)pyridine
EINECS	Contact for details

Quality Control

Our n-Formylnornicotine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and determination of residual solvents to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.