Description

1-Fluoro-5-Methoxy-2,4-Dinitro-Benzene is a specialized aromatic nitro compound featuring a unique substitution pattern of fluorine and methoxy groups. This compound serves as a versatile and critical building block in advanced organic synthesis, particularly for the development of complex molecules. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic cores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its reactive nitro groups for further functionalization.
• Dye and Pigment Manufacturing: Serves as an intermediate for synthesizing specialized azo dyes and other colorants due to its electron-withdrawing nitro substituents.
• Material Science Research: Employed in the development of novel organic electronic materials and liquid crystals, where its specific substitution pattern can tune electronic properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl structures.
• Nucleophilic Aromatic Substitution: The activated fluorine atom makes it an excellent substrate for reactions with various nucleophiles to introduce new functional groups.

Basic Information

Product Name	1-Fluoro-5-Methoxy-2,4-Dinitro-Benzene
CAS No.	394-18-3
Molecular Formula	C7H5FN2O5
Molecular Weight	216.13 g/mol
Synonyms	2,4-Dinitro-5-fluoroanisole; 5-Fluoro-2,4-dinitroanisole; 1-Fluoro-2,4-dinitro-5-methoxybenzene; 5-Methoxy-2,4-dinitrofluorobenzene; Benzene, 1-fluoro-5-methoxy-2,4-dinitro-; FDNB (context-specific); 394-18-3; NSC 403697
EINECS	206-900-5

Quality Control

Our 1-Fluoro-5-Methoxy-2,4-Dinitro-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets precise customer specifications. Certificates of Analysis (COA) detailing all test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.