Description

2-Chloro-3,5-Dinitrobenzotrifluoride is a high-value, multi-functional aromatic intermediate characterized by its unique combination of chloro, nitro, and trifluoromethyl substituents. This compound is essential for synthesizing advanced materials and active pharmaceutical ingredients (APIs) due to its electron-deficient aromatic ring, which facilitates selective nucleophilic substitution reactions. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas like kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and stability.
• Dye and Pigment Manufacturing: Serves as a precursor for high-performance, light-fast dyes and pigments.
• Material Science: Intermediate in the development of liquid crystals, organic semiconductors, and polymers with specific electronic properties.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating complex biaryl structures.
• Research & Development: A versatile reagent for academic and industrial research in organic synthesis and medicinal chemistry.

Basic Information

Product Name	2-Chloro-3,5-Dinitrobenzotrifluoride
CAS No.	392-95-0
Molecular Formula	C7H2ClF3N2O4
Molecular Weight	270.55 g/mol
Synonyms	1-Chloro-2,4-dinitro-5-(trifluoromethyl)benzene; 2,4-Dinitro-1-chloro-5-(trifluoromethyl)benzene; Benzene, 1-chloro-2,4-dinitro-5-(trifluoromethyl)-; 3,5-Dinitro-2-chlorobenzotrifluoride; 2-Chloro-α,α,α-trifluoro-3,5-dinitrotoluene
EINECS	206-882-6

Quality Control

Our 2-Chloro-3,5-Dinitrobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.