Description

Desoximetasone is a synthetic corticosteroid belonging to the glucocorticoid class, known for its potent anti-inflammatory and immunosuppressive properties. This high-purity active pharmaceutical ingredient (API) is critical for formulating effective topical dermatological treatments. It is primarily required by pharmaceutical manufacturers and research institutions focused on developing and producing advanced corticosteroid-based medications.

Application

• Topical Corticosteroid Formulations: Primary use in creams, ointments, gels, and lotions for treating inflammatory skin conditions such as psoriasis, eczema, and dermatitis.
• Dermatological Research: Serves as a key reference standard and active compound in preclinical and clinical research for new topical anti-inflammatory therapies.
• Pharmaceutical Intermediates: Used in the synthesis of more complex steroid molecules or prodrugs within specialized pharmaceutical chemistry.
• Veterinary Medicine: Application in topical preparations for managing inflammatory skin disorders in animals.

Basic Information

Product Name	Desoximetasone
CAS No.	382-67-2
Molecular Formula	C22H29FO4
Molecular Weight	376.46 g/mol
Synonyms	9α-Fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione; Desoxymethasone; 9-Fluoro-11β,21-dihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione; Topisolon; Esperson; Dermabet; Sterax; Ibaril
EINECS	206-836-2

Quality Control

Our Desoximetasone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. Certificates of Analysis (COA) detailing purity, related substances, and identity are provided with every shipment. We can support compliance with major pharmacopoeial standards such as USP and EP upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.