Description

Fccp CAS NO 370-86-5 is a potent and highly specific chemical agent widely recognized for its role as a mitochondrial uncoupler. This compound is critical for researchers and industrial scientists studying cellular bioenergetics, metabolic pathways, and oxidative stress. It is an essential tool for the pharmaceutical, biotechnology, and life science research industries, where precise control over mitochondrial function is required for drug discovery and toxicology studies.

Application

• Biochemical Research: Primary use as a protonophore to uncouple oxidative phosphorylation in mitochondria, facilitating studies on ATP production, oxygen consumption, and metabolic rates.
• Pharmaceutical Screening: Employed in high-throughput assays to investigate compounds that modulate mitochondrial activity and to model mitochondrial dysfunction.
• Cell Biology & Physiology: Used to induce metabolic stress, study reactive oxygen species (ROS) generation, and probe mechanisms of apoptosis and cell death.
• Toxicology Studies: Serves as a reference uncoupler to assess the potential mitochondrial toxicity of new chemical entities and environmental pollutants.
• Bioenergetics Profiling: A key reagent in Seahorse XF Analyzer and other flux analysis platforms to measure real-time cellular metabolic function.

Basic Information

Product Name	Fccp
CAS No.	370-86-5
Molecular Formula	C8H4ClF3N2O
Molecular Weight	236.58 g/mol
Synonyms	Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone; FCCP; Carbonyl cyanide p-trifluoromethoxyphenylhydrazone; Uncoupler FCCP; CF3OC6H4NHN=C(CN)Cl; 1-[5-(Trifluoromethoxy)-1H-indol-3-yl]piperidine; (Trifluoromethoxy)phenylhydrazonopropanedinitrile
EINECS	206-741-2

Quality Control

Our Fccp is produced and tested to meet the stringent requirements of research and industrial applications. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and identity confirmation by spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure traceability and batch-to-batch consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.