Description

Sodium Cholate is the sodium salt of cholic acid, a primary bile acid essential for the emulsification and absorption of dietary fats and fat-soluble vitamins. This high-purity biochemical is a critical reagent in life science research and pharmaceutical development due to its role as a biological detergent and membrane-disrupting agent. It is primarily utilized by manufacturers and researchers in the pharmaceutical, diagnostic, and biotechnology sectors for applications ranging from cell culture to drug formulation.

Application

• Pharmaceutical Excipient: Used as a solubilizing and absorption-enhancing agent in oral and injectable drug formulations.
• Cell Biology & Biochemistry: Essential for the isolation and purification of membrane proteins and organelles by solubilizing lipid bilayers.
• Diagnostic Reagents: A key component in clinical chemistry kits for liver function tests and enzymatic assays.
• Microbiology & Cell Culture: Employed in selective media and as a detergent in virology research.
• Lipid & Bile Acid Research: Serves as a standard reference material in analytical studies of bile acid metabolism.
• Industrial Applications: Used in certain emulsification and solubilization processes within specialty chemical manufacturing.

Basic Information

Product Name	Sodium Cholate
CAS No.	361-09-1
Molecular Formula	C24H39NaO5
Molecular Weight	430.56 g/mol
Synonyms	Cholic Acid Sodium Salt; Sodium Cholic Acid; 3α,7α,12α-Trihydroxy-5β-cholan-24-oic Acid Sodium Salt; Cholate Sodium Salt; Cholalic Acid Sodium Salt; Sodium 3,7,12-Trihydroxycholanate; Taurocholate (related compound); Glycocholate (related compound)
EINECS	206-643-6

Quality Control

Our Sodium Cholate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material compliant with relevant pharmacopeial standards (e.g., USP/NF) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition (Sulfated Ash)	15.0% - 17.0%
Heavy Metals (as Pb)	≤ 20 ppm
Specific Rotation [α]20/D	+37.0° to +41.0°
Microbial Limits	Meets specified criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.