Description

Glycodeoxycholic Acid is a secondary bile acid conjugate, formed by the conjugation of deoxycholic acid with glycine. This compound is a critical biochemical reagent and a key intermediate in the study of bile acid metabolism and signaling pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in metabolic disease research, drug discovery, and the development of diagnostic assays. Our supply ensures high purity and batch-to-batch consistency, meeting the stringent requirements of advanced scientific and industrial applications.

Application

• Biochemical Research: A vital standard and intermediate for studying bile acid synthesis, enterohepatic circulation, and their role as signaling molecules.
• Pharmaceutical Development: Serves as a reference compound and a potential starting material for the synthesis of novel therapeutic agents targeting metabolic disorders.
• Diagnostic Reagents: Used in the calibration and development of clinical diagnostic kits for liver function and bile acid-related pathologies.
• Cell Culture & Microbiology: Employed in specialized cell culture media and as a biochemical tool to modulate FXR (Farnesoid X receptor) and other nuclear receptor pathways in vitro.
• Analytical Standards: Essential high-purity standard for quantitative analysis (e.g., HPLC, LC-MS) in bioanalytical laboratories and quality control.

Basic Information

Product Name	Glycodeoxycholic Acid
CAS No.	360-65-6
Molecular Formula	C₂₆H₄₃NO₅
Molecular Weight	449.63 g/mol
Synonyms	N-[(3α,5β,12α)-3,12-Dihydroxy-24-oxocholan-24-yl]glycine; Glycochenodeoxycholic Acid (common isomer reference); GDCA; Deoxycholylglycine; Glycodeoxycholate; N-Glycyldeoxycholic Acid; 3α,12α-Dihydroxy-5β-cholan-24-oyl Glycine
EINECS	206-638-5

Quality Control

Our Glycodeoxycholic Acid is manufactured under a strict quality management system. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-grade specifications suitable for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your technical requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.