Description

Harmine Hydrochloride is a high-purity alkaloid derivative widely recognized for its role as a selective and potent inhibitor of monoamine oxidase A (MAO-A). This compound is essential for biochemical and pharmacological research, serving as a critical reference standard and a key intermediate in the development of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on neuroscience, oncology, and metabolic studies.

Application

• Biochemical Research: Used as a selective MAO-A inhibitor in enzymatic studies and receptor binding assays.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development of central nervous system (CNS) and anti-cancer drugs.
• Academic Research: Employed in university and institutional labs for studying neurochemistry, cell signaling pathways, and apoptosis.
• Analytical Reference Standard: Provides a certified benchmark for quality control and method validation in HPLC and LC-MS analysis.
• Precursor Synthesis: Acts as a starting material for the synthesis of more complex harmala alkaloid derivatives and analogs.

Basic Information

Product Name	Harmine Hydrochloride
CAS No.	343-27-1
Molecular Formula	C13H12N2O·HCl
Molecular Weight	248.71 g/mol
Synonyms	7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole hydrochloride; Banisterine hydrochloride; Telepathine hydrochloride; Yageine hydrochloride; Leucoharmine hydrochloride; Harmine HCl; 7-Methoxyharman hydrochloride
EINECS	Contact for details

Quality Control

Our Harmine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent controls for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.