Description

Retinoic Acid, Methyl Ester is a synthetic derivative of vitamin A, specifically the methyl ester of all-trans retinoic acid. This compound is a crucial intermediate and active ingredient in advanced pharmaceutical research and cosmetic science, valued for its defined chemical structure and biological activity. It is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical, dermatological, and life science sectors for developing novel therapeutic and cosmetic formulations.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of retinoid-based drugs for treating dermatological conditions like acne and psoriasis.
• Cosmetic Actives R&D: Used in the research and development of anti-aging and skin-renewal serums and creams.
• Biochemical Research: Serves as a reference standard and ligand in studies of retinoid receptors (RARs/RXRs) and cellular differentiation pathways.
• Cell Culture & Differentiation Studies: Employed in *in vitro* models to induce and study cell differentiation, particularly in stem cell research.
• Organic Synthesis: Acts as a versatile synthon for creating more complex retinoid analogs and novel chemical entities.

Basic Information

Product Name	Retinoic Acid, Methyl Ester
CAS No.	339-16-2
Molecular Formula	C21H30O2
Molecular Weight	314.46 g/mol
Synonyms	Methyl Retinoate; all-trans-Methyl Retinoate; Retinoic Acid Methyl Ester; Methyl all-trans-Retinoate; Tretinoin Methyl Ester; Vitamin A Acid Methyl Ester; 9,13-Dimethyl-7-(1,1,5-trimethyl-6-cyclohexen-5-yl)-7,9,11,13-nonatetraenoic Acid Methyl Ester
EINECS	206-398-2

Quality Control

Our Retinoic Acid, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity standards suitable for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, isomer purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC, Area %)	≥ 98.0% (all-trans isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.