Description

Homovanillic Acid is a key phenolic acid and a major metabolite of dopamine, serving as a critical biochemical marker in neurological and clinical research. Its high purity and stability are essential for ensuring accurate analytical results in diagnostic assays and metabolic studies. This compound is primarily utilized by the pharmaceutical, biotechnology, and diagnostic industries for research, method development, and as a reference standard.

Application

• Biochemical Research & Diagnostic Assays: Used as a primary standard for the quantification of catecholamines and their metabolites in HPLC and LC-MS methods.
• Clinical Diagnostics: A crucial biomarker for assessing dopamine metabolism in patients with neurological disorders such as Parkinson's disease and neuroblastoma.
• Pharmaceutical Development: Employed in pharmacokinetic and metabolic pathway studies during drug discovery and development phases.
• Reference Standard: Serves as a certified reference material (CRM) for quality control in analytical laboratories to ensure method accuracy and compliance.
• Enzymatic Studies: Utilized as a substrate or product in enzymatic assays related to neurotransmitter synthesis and degradation.

Basic Information

Item	Detail
Product Name	Homovanillic Acid
CAS No.	306-08-1
Molecular Formula	C9H10O4
Molecular Weight	182.17 g/mol
Synonyms	4-Hydroxy-3-methoxyphenylacetic Acid; HVA; Vanillacetic Acid; 3-Methoxy-4-hydroxyphenylacetic Acid; 4-Hydroxy-3-methoxybenzeneacetic Acid; (4-Hydroxy-3-methoxyphenyl)acetic Acid
EINECS	206-167-2

Quality Control

Our Homovanillic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and melting point, and residual solvent analysis to ensure it meets high-purity standards suitable for research and diagnostic use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Melting Point	142°C - 146°C
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.