Description

Iodoacetic Acid Sodium Salt is a versatile alkylating agent and a key biochemical reagent used to inhibit enzymes by modifying cysteine residues. This compound is essential for researchers and manufacturers requiring precise chemical modification in biological systems. It is primarily utilized in proteomics research, biochemical studies, and as a critical intermediate in pharmaceutical synthesis for global industrial and academic laboratories.

Application

• Biochemical Research: As a potent sulfhydryl group alkylating agent to irreversibly inhibit enzymes like glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in metabolic studies.
• Proteomics & Protein Chemistry: For the selective modification of cysteine residues in peptides and proteins to study structure-function relationships.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of more complex molecules for drug discovery and development.
• Cell Biology Studies: Used to investigate glycolysis and cellular energy metabolism pathways by inhibiting specific enzymatic steps.
• Cross-linking Agent: Employed in the preparation of modified biomaterials and for creating protein conjugates.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Iodoacetic Acid Sodium Salt
CAS No.	305-53-3
Molecular Formula	C2H2INaO2
Molecular Weight	207.93 g/mol
Synonyms	Sodium Iodoacetate; Iodoacetic Acid Sodium Salt; Monosodium Iodoacetate; Sodium 2-Iodoacetate; IAA Sodium Salt; 2-Iodoacetic Acid Sodium Salt; NSC 7480; Iodoacetate Sodium Salt
EINECS	206-165-7

Quality Control

Our Iodoacetic Acid Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and industrial applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.