Description

Lasiocarpine is a pyrrolizidine alkaloid of significant interest in biochemical and pharmaceutical research. This compound serves as a critical reference standard and intermediate for studying hepatotoxicity and developing analytical methods. It is primarily utilized by research institutions, pharmaceutical R&D departments, and quality control laboratories focused on natural product chemistry and toxicology. Our supply ensures high purity and batch-to-batch consistency for reliable experimental results.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of pyrrolizidine alkaloids in herbal medicines and dietary supplements.
• Toxicological Research: A key compound in studies investigating the mechanisms of hepatotoxicity and genotoxicity associated with pyrrolizidine alkaloid exposure.
• Analytical Method Development: Serves as a critical standard for developing and validating analytical methods such as HPLC, LC-MS, and GC-MS for contaminant screening.
• Biochemical Studies: Employed in research exploring the metabolic pathways and bioactivation of hepatotoxic alkaloids.
• Quality Control & Safety Testing: Essential for laboratories ensuring the safety of botanical raw materials, teas, and herbal products by testing for harmful alkaloid content.

Basic Information

Product Name	Lasiocarpine
CAS No.	303-34-4
Molecular Formula	C21H33NO7
Molecular Weight	411.49 g/mol
Synonyms	Lasiocarpine; 7β-Angeloyloxy-1α-methyl-8α-pyrrolizidine-1β,8β-diol; 7β-(2-Methylbutyryloxy)-1α-methyl-8α-pyrrolizidine-1β,8β-diol; Lasiocarpin; Heliotrine 7-angelate; NSC 32918; (1R,7aR)-1-[(2S)-2-Hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutyl]-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl (2Z)-2-methylbut-2-enoate
EINECS	206-144-5

Quality Control

Our Lasiocarpine is produced and handled under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research and reference standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.