Description

Aconitine CAS NO 302-27-2 is a highly potent diterpenoid alkaloid derived from plants of the *Aconitum* genus, such as monkshood. This compound is of significant interest in biochemical and pharmacological research due to its complex structure and potent activity on voltage-gated sodium channels. It serves as a critical reference standard and research chemical for toxicology studies, forensic analysis, and the development of novel therapeutic agents. Industries including pharmaceutical R&D, analytical laboratories, and academic institutions rely on high-purity aconitine for precise scientific investigations.

Application

• Pharmaceutical Research & Development: Used as a reference standard in the study of neurotoxins, sodium channel modulators, and for the development of potential analgesic or antiarrhythmic agents.
• Analytical Chemistry & Toxicology: Serves as a critical calibrant and control substance in forensic toxicology, poison control analysis, and the detection of plant-based toxins in food and herbal products.
• Biochemical Studies: Employed in electrophysiology and molecular biology research to investigate the mechanism of action on neuronal ion channels and cellular signaling pathways.
• Academic & Educational Use: Utilized in university laboratories for advanced teaching and research in natural product chemistry, pharmacology, and toxicology.
• Quality Control & Standardization: Acts as a primary standard for the assay and quality control of related herbal extracts and traditional medicines, ensuring batch-to-batch consistency.

Basic Information

Product Name	Aconitine
CAS No.	302-27-2
Molecular Formula	C34H47NO11
Molecular Weight	645.74 g/mol
Synonyms	Aconitine; (1α,3α,6α,14α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14-tetrol 8-acetate 14-benzoate; Aconitin; Acetylbenzoylaconine; NSC 209816
EINECS	206-121-7

Quality Control

Our Aconitine is produced and handled under strict quality management protocols to ensure the highest standards of purity and consistency for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods (IR, NMR) for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results. We adhere to relevant industry guidelines to support your compliance needs in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be kept under anhydrous conditions. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.