Description

cis-4,7,10,13,16,19-Docosahexaenoic Acid Methyl Ester is the methyl ester derivative of the essential ω-3 fatty acid DHA (docosahexaenoic acid). This high-purity intermediate is critical for ensuring consistent quality and bioavailability in advanced nutritional and pharmaceutical formulations. It is primarily utilized by manufacturers in the nutraceutical, pharmaceutical, and research sectors for the production of standardized supplements, active pharmaceutical ingredients (APIs), and as a critical reference standard.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of high-purity DHA for prescription and over-the-counter pharmaceutical products targeting cardiovascular and neurological health.
• Nutraceutical Formulation: Used in the manufacture of concentrated ω-3 supplements, softgel capsules, and functional foods requiring a standardized and stable esterified DHA source.
• Biomedical Research: Serves as a critical standard and reagent in lipidomics, metabolic studies, and research on inflammation, neuroprotection, and cell membrane fluidity.
• Reference Standard: Employed in analytical laboratories for the calibration of equipment (HPLC, GC) and quality control testing of DHA-containing raw materials and finished products.
• Cosmetic Ingredients: Incorporated into advanced skincare formulations for its potential anti-inflammatory and skin-barrier supporting properties.
• Animal Nutrition: Used in premium aquafeed and pet nutrition to enhance the DHA content, supporting healthy development and immune function.

Basic Information

Product Name	cis-4,7,10,13,16,19-Docosahexaenoic Acid Methyl Ester
CAS No.	301-01-9
Molecular Formula	C23H34O2
Molecular Weight	342.51 g/mol
Synonyms	DHA Methyl Ester; Methyl Docosahexaenoate; Methyl (4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-Docosahexaenoate; Methyl all-cis-4,7,10,13,16,19-Docosahexaenoate; Cervonic Acid Methyl Ester; 22:6(n-3) Methyl Ester; ω-3 Fatty Acid Methyl Ester
EINECS	206-103-9

Quality Control

Our cis-4,7,10,13,16,19-Docosahexaenoic Acid Methyl Ester is produced and tested under a strict quality management system. Each batch is analyzed to ensure it meets stringent specifications for identity, purity, and composition, suitable for demanding applications. Certificates of Analysis (COA) detailing results from GC, HPLC, and other relevant tests are provided to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) at 2-8°C to minimize oxidation and maintain stability. Keep away from heat and open flames. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow oil
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 95.0%
DHA Content (as methyl ester)	≥ 90.0%
Peroxide Value	≤ 5.0 meq/kg
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.