Description

Arecoline Hydrobromide is a quaternary ammonium alkaloid salt, a key derivative of the areca nut. This compound is of significant interest in pharmacological research due to its activity as a muscarinic acetylcholine receptor agonist. It serves as a critical reference standard and building block for researchers and manufacturers in the pharmaceutical and life sciences sectors. Arecoline Hydrobromide CAS NO 300-08-3 is essential for developing and validating analytical methods and studying cholinergic pathways.

Application

• Pharmaceutical Reference Standard: Used as a primary standard for quality control and assay calibration in drug development and manufacturing.
• Neuroscience Research: A vital tool for studying the cholinergic system, receptor binding, and neurological functions in preclinical models.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic precursor in the production of more complex therapeutic agents.
• Analytical Chemistry: Employed in method development and validation for HPLC, LC-MS, and other chromatographic techniques.
• Biochemical Assays: Used in enzymatic and receptor-based in vitro assays to investigate mechanism of action.
• Veterinary Medicine Research: Applied in studies exploring parasympathomimetic effects and potential therapeutic applications.

Basic Information

Product Name	Arecoline Hydrobromide
CAS No.	300-08-3
Molecular Formula	C8H13NO2 • HBr
Molecular Weight	236.11 g/mol
Synonyms	Arecoline HBr; Arecoline Hydrobromide Salt; 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic Acid Methyl Ester Hydrobromide; Methyl Arecaidine Hydrobromide; Arecolinium Bromide; N-Methylguvacine Methyl Ester Hydrobromide; Arecoline Bromohydrate
EINECS	206-096-1

Quality Control

Our Arecoline Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.