Description

2,2'-Bi-1H-Imidazole, 1,1'-Bis[3-(1,1-Dimethylethyl)Phenyl]-4,4',5,5'-Tetrahydro-4,4'-Bis(2-Methylpropyl)-, (4S,4'S)- is a sophisticated, stereochemically defined chiral ligand and building block of significant interest in advanced chemical synthesis. Its value lies in its ability to impart high selectivity and efficiency in catalytic processes, particularly in the synthesis of complex, optically active molecules. This compound is primarily needed by R&D and process development teams within the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and fine chemicals.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, such as hydrogenation, cross-coupling, and cycloaddition.
• A key intermediate or building block in the synthesis of novel pharmaceutical candidates, especially those requiring specific stereochemistry.
• Use in the research and development of advanced agrochemicals to create enantiomerically pure active ingredients.
• Potential application in the synthesis of functional materials, including chiral polymers or metal-organic frameworks (MOFs).
• As a research chemical for studying structure-activity relationships and developing new catalytic systems in academic and industrial laboratories.

Basic Information

Item	Details
Product Name	2,2'-Bi-1H-Imidazole, 1,1'-Bis[3-(1,1-Dimethylethyl)Phenyl]-4,4',5,5'-Tetrahydro-4,4'-Bis(2-Methylpropyl)-, (4S,4'S)-
CAS No.	2828440-25-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(4S,4'S)-1,1'-Bis[3-tert-butylphenyl]-4,4'-diisobutyl-4,4',5,5'-tetrahydro-2,2'-bi-1H-imidazole; Chiral Bi-Imidazole Ligand; 1,1'-Bis(3-tert-butylphenyl)-4,4'-bis(2-methylpropyl)-4,4',5,5'-tetrahydro-2,2'-biimidazole, (4S,4'S)-; (S,S)-1,1'-Di(3-tert-butylphenyl)-4,4'-diisobutyl-4,4',5,5'-tetrahydro-2,2'-biimidazole; Tetrahydrobiimidazole Derivative; Asymmetric Catalyst Ligand
EINECS	Contact for details

Quality Control

Every batch of our 2,2'-Bi-1H-Imidazole derivative is produced and tested under a strict quality management system. We ensure high chiral purity and chemical consistency through advanced analytical techniques like chiral HPLC and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; prolonged exposure to air or light may lead to degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.