Description

L-Glutamic Acid, n-[4-[(2-Amino-3,4-Dihydro-7-Methyl-4-Oxo-6-Pteridinyl)Amino]Benzoyl]- is a high-purity, complex pteridine derivative and glutamic acid conjugate, representing a critical advanced intermediate in modern pharmaceutical research and development. This compound is essential for its role in the synthesis of targeted therapeutic agents, particularly in oncology and metabolic disease research, where precise molecular structure is paramount. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and advanced chemical synthesis facilities focused on developing novel drug candidates and biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel folate analogs and targeted chemotherapeutic agents.
• Biochemical Research: Used as a precursor or reference standard in enzymatic studies and metabolic pathway investigation.
• Antifolate Drug Development: Serves as a core structure in the research and development of dihydrofolate reductase (DHFR) inhibitors.
• High-Value Fine Chemical Synthesis: Employed in multi-step organic synthesis for producing complex, high-purity molecules for clinical trials.
• Reference Standard: Utilized in analytical laboratories for method development, validation, and quality control of related pharmaceutical products.

Basic Information

Product Name	L-Glutamic Acid, n-[4-[(2-Amino-3,4-Dihydro-7-Methyl-4-Oxo-6-Pteridinyl)Amino]Benzoyl]-
CAS No.	2734707-85-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-[4-[[(2-Amino-3,4-dihydro-7-methyl-4-oxo-6-pteridinyl)amino]benzoyl]-L-glutamic acid; 6-[(4-[[(1S)-1,5-Dicarboxy-3-oxopentyl]amino]phenyl)amino]-7-methyl-3,4-dihydro-2-pteridinamine 4-oxide; Pteroic acid glutamic acid conjugate derivative; 7-Methyl-6-(p-aminobenzamido)glutamic pteridine; Advanced folate synthesis intermediate; L-Glu-Pteroate analog; DHFR inhibitor precursor
EINECS	Contact for details

Quality Control

Our L-Glutamic Acid, n-[4-[(2-Amino-3,4-Dihydro-7-Methyl-4-Oxo-6-Pteridinyl)Amino]Benzoyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content	≤ 5.0% (KF)
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.