Description

m-Peg9-Cooh is a monodisperse polyethylene glycol (PEG) derivative featuring a carboxylic acid functional group at one terminus. This precise chemical structure makes it a highly valuable heterobifunctional linker for bioconjugation and pharmaceutical development. It is essential for researchers and manufacturers in the life sciences sector who require reliable, high-purity building blocks for creating PEGylated therapeutics, diagnostic agents, and advanced biomaterials.

Application

• Bioconjugation Linker: Used to covalently attach peptides, proteins, or antibodies to other molecules, surfaces, or nanoparticles via its reactive carboxyl group.
• Pharmaceutical PEGylation: Serves as a key intermediate for modifying therapeutic proteins and peptides to enhance solubility, prolong circulation half-life, and reduce immunogenicity.
• Diagnostic Reagent Synthesis: Employed in the development of contrast agents and fluorescent probes for imaging applications.
• Polymer Chemistry: Acts as a macroinitiator or monomer for synthesizing functionalized, biocompatible block copolymers and hydrogels.
• Surface Modification: Used to create hydrophilic, non-fouling coatings on medical devices and biosensor surfaces.
• Drug Delivery Systems: Incorporated into the design of micelles, liposomes, and dendrimers for targeted drug delivery.

Basic Information

Product Name	m-Peg9-Cooh
CAS No.	2576495-35-5
Molecular Formula	C₂₀H₄₀O₁₁
Molecular Weight	456.53 g/mol
Synonyms	9-Aza-3,6,12,15,18,21,24,27,30-nonaoxahentriacontan-31-oic acid; mPEG9-acid; α-Methyl-ω-carboxy-nonaethylene glycol; Monomethoxy PEG9 carboxylic acid; HOOC-PEG9-OMe; Carboxymethyl PEG9 methyl ether; 2-[2-[2-[2-[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid; PEG9-CH2COOH
EINECS	Contact for details

Quality Control

Our m-Peg9-Cooh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, NMR for structural confirmation, and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.