Description

Uridine 5'-Triphosphate, Ammonium Salt (5,6-D2, 98%) Chem Pur. >90% (In Soln) is a deuterium-labeled, high-purity nucleotide essential for advanced biochemical research and diagnostic applications. This compound is specifically designed for use as a stable, non-radioactive tracer in metabolic pathway studies, enzyme kinetics, and NMR spectroscopy. It is a critical reagent for pharmaceutical R&D, academic research, and the development of molecular diagnostics, where precise tracking of nucleotide incorporation is required. The product is supplied as a solution to ensure stability and convenience for laboratory use.

Application

• Metabolic Flux Analysis & Tracer Studies: Used as a deuterium-labeled substrate to track and quantify nucleotide metabolism in cell cultures and in vitro systems.
• Enzyme Mechanism & Kinetics Research: Serves as a specialized substrate for studying the activity and inhibition of kinases, polymerases, and other nucleotide-processing enzymes.
• NMR Spectroscopy: The deuterium label provides a non-perturbing probe for structural and dynamic studies of biomolecules and their interactions.
• Pharmaceutical Development: Employed in the research and development of antiviral and anticancer agents that target nucleotide synthesis pathways.
• Diagnostic Assay Development: Used in the formulation of high-sensitivity kits for detecting specific enzymatic activities or nucleic acid synthesis.
• Biochemical Standard: Acts as a certified reference material for the calibration of analytical instruments like HPLC and LC-MS in quality control laboratories.

Basic Information

Product Name	Uridine 5'-Triphosphate, Ammonium Salt (5,6-D2, 98%) Chem Pur. >90% (In Soln)
CAS No.	2483831-89-4
Molecular Formula	C9H11D2N2O15P3 · xNH3
Molecular Weight	Contact for details
Synonyms	5,6-Dideuterouridine 5'-triphosphate ammonium salt; [5,6-D2]UTP ammonium salt; Deuterated UTP; d2-UTP; Uridine-5'-triphosphate-d2 ammonium salt; UTP-d2 (ammonium); 2',3',5'-Tri-O-phosphono-5,6-dideuterouridine ammonium salt
EINECS	Contact for details

Quality Control

Every batch of our Uridine 5'-Triphosphate, Ammonium Salt (5,6-D2) is manufactured and analyzed under strict quality protocols to ensure the highest standards of purity and isotopic enrichment. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for assay, isotopic purity, and solvent content.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. The solution should be kept in aliquots to avoid repeated freeze-thaw cycles. Handle under inert conditions if the container is opened frequently to minimize degradation.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	>90% (in solution)
Isotopic Purity (D2)	≥98%
Chemical Purity (HPLC)	≥98%
pH	6.0 - 8.0 (in solution)
Solvent	Deuterium Oxide (D2O) or specified buffer
Bacterial Endotoxins	<1.0 EU/mL (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.