Description

Cytidine 5'-Triphosphate, Ammonium Salt (D8, 97%+) Chem Pur. >90% (In Soln) is a high-purity, deuterium-labeled nucleotide essential for advanced biochemical research and pharmaceutical development. This compound is critical for applications requiring precise isotopic tracing, offering superior stability and minimal background interference in sensitive assays. It is primarily utilized by research institutions, diagnostic developers, and pharmaceutical companies engaged in metabolic pathway studies, enzyme kinetics, NMR spectroscopy, and the synthesis of labeled oligonucleotides.

Application

• Biochemical Research & NMR Spectroscopy: Used as a deuterium-labeled substrate or tracer for studying enzyme mechanisms, metabolic flux analysis, and protein-nucleic acid interactions.
• Diagnostic Assay Development: Serves as a critical component in the formulation of kits for detecting viral RNA polymerases or other nucleotide-dependent enzymes.
• Pharmaceutical R&D (Pre-clinical): Employed in the synthesis of isotopically labeled probes and analogs for drug discovery and pharmacokinetic studies.
• Virology & Antiviral Research: Acts as a substrate in studies targeting viral replication enzymes, such as RNA-dependent RNA polymerases.
• Synthesis of Labeled Oligonucleotides: A key raw material for producing deuterium-labeled DNA or RNA strands used in advanced biophysical and structural biology techniques.

Basic Information

Product Name	Cytidine 5'-Triphosphate, Ammonium Salt (D8, 97%+) Chem Pur. >90% (In Soln)
CAS No.	2483831-66-7
Molecular Formula	C9D8H8N3O14P3 · xNH3
Molecular Weight	~503.1 (Free acid, D8) + (NH4 salt adjustment)
Synonyms	CTP Ammonium Salt (D8); Deuterated Cytidine Triphosphate; [D8]-CTP; Cytidine-5'-triphosphate-1',2',3',4',5',6',1'',2''-d8 ammonium salt; Ammonium cytidine 5'-(tetrahydrogen triphosphate) (D8); Perdeuterated CTP; CTP-d8; 5'-CTP-(NH4)2-d8
EINECS	Contact for details

Quality Control

Every batch of our deuterium-labeled Cytidine 5'-Triphosphate is manufactured and tested under stringent quality systems. We guarantee a minimum isotopic enrichment of 97% D (97%+) and a chemical purity of >90% in solution, as determined by advanced analytical techniques including NMR and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, solvent content, and absence of critical impurities is provided with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. The product is supplied in solution and is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles to maintain optimal performance and purity.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to slightly yellow
Identification (NMR/HPLC)	Conforms to reference standard
Isotopic Enrichment (D)	≥ 97%
Assay (HPLC)	> 90% (CTP basis in specified solvent)
pH (in solution)	6.0 - 8.0
Solvent Content (Residual Solvent)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.