Description

Pc-Peg11-Azide is a functionalized, azide-terminated polyethylene glycol (PEG) derivative designed for advanced bioconjugation and materials science applications. This compound matters for its role as a critical linker in click chemistry, enabling the precise and efficient attachment of biomolecules, polymers, or other functional groups under mild, aqueous conditions. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and nanotechnology sectors for developing targeted drug delivery systems, diagnostic probes, and functionalized hydrogels.

Application

• Bioconjugation Linker: Used in copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry to conjugate peptides, proteins, antibodies, or oligonucleotides to various carriers or surfaces.
• Drug Delivery System Fabrication: Serves as a key component for synthesizing PEGylated prodrugs or creating targeted nanocarriers to improve drug solubility, stability, and pharmacokinetics.
• Surface Functionalization: Enables the modification of nanoparticles, biosensors, and medical device surfaces with bioactive molecules to enhance specificity and biocompatibility.
• Polymer Chemistry: Acts as a macro-initiator or chain extender in the synthesis of functional block copolymers and cross-linked hydrogel networks for tissue engineering.
• Diagnostic Reagent Development: Utilized to label biomolecules with fluorescent dyes or other reporter groups for use in immunoassays, flow cytometry, and in vivo imaging.
• Chemical Biology Probes: Facilitates the creation of activity-based probes for studying enzyme function, protein-protein interactions, and cellular pathways.

Basic Information

Product Name	Pc-Peg11-Azide
CAS No.	2353409-89-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PC-PEG11-N3; Propargyl Carbamate-PEG11-Azide; Azido-PEG11-Propargyl Carbamate; 11-Azido-3,6,9-trioxaundecan-1-amine, N-(prop-2-yn-1-yl)carbamate; PEG11 Azide Alkyne Linker; Heterobifunctional PEG Linker, Azide-Alkyne; Alkyne-PEG11-Azide; Propargyl-PEG11-Azide
EINECS	Contact for details

Quality Control

Our Pc-Peg11-Azide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product at -20°C or below under desiccant. The compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Functional Group Assay (Azide)	≥ 90%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.