Description

Propargyl-Peg2-β-D-Glucose is a functionalized carbohydrate derivative designed for advanced bioconjugation and chemical biology applications. This compound is engineered to provide a click chemistry handle, enabling precise and efficient covalent attachment to azide-functionalized molecules under mild, bio-orthogonal conditions. It is a critical reagent for researchers and manufacturers in pharmaceutical development, proteomics, and diagnostic assay production who require reliable, high-purity building blocks for complex molecular assembly.

Application

• Bioconjugation & Click Chemistry: Serves as a key intermediate for attaching sugars, peptides, or other biomolecules to surfaces, polymers, or proteins via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Pharmaceutical Research: Used in the synthesis of antibody-drug conjugates (ADCs), targeted drug delivery systems, and novel glycoconjugate therapeutics.
• Diagnostic Development: Functionalizes surfaces for biosensors, microarrays, and lateral flow assays to improve detection sensitivity and specificity.
• Glycobiology Studies: Acts as a chemical probe for studying carbohydrate-protein interactions, enzyme activity, and metabolic labeling.
• Polymer & Material Science: Incorporated into hydrogels, smart materials, and functional coatings to introduce bioactivity and specific binding sites.
• Chemical Biology Toolkits: Supplied as a high-purity building block for creating custom chemical libraries and probes for high-throughput screening.

Basic Information

Product Name	Propargyl-Peg2-β-D-Glucose
CAS No.	2353409-73-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Propargyl-PEG2-β-D-Glucose; 1-O-(2-[2-(2-Propyn-1-yloxy)ethoxy]ethyl)-β-D-glucopyranose; β-D-Glucose, 1-O-[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]-; Propargyl-PEG2-Glucose; Alkyne-PEG2-Glucose; Click Chemistry Glucose Derivative; Functionalized D-Glucose; Glycosyl Alkyne Reagent
EINECS	Contact for details

Quality Control

Every batch of Propargyl-Peg2-β-D-Glucose is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure high purity and batch-to-batch consistency through techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.