Description

Nqo1 Substrate CAS NO 2304503-05-5 is a specialized biochemical compound designed for research into the NAD(P)H:quinone oxidoreductase 1 (NQO1) enzyme pathway. This substrate is critical for studying cellular redox regulation, chemoprotection, and the bioactivation of quinone-based prodrugs. It is an essential tool for pharmaceutical researchers, academic institutions, and biotechnology companies focused on oncology, neuroprotection, and metabolic disease research.

Application

• Enzyme Activity Assays: Used as a specific substrate in spectrophotometric or fluorometric assays to quantify NQO1 enzyme activity in cell lysates and tissue homogenates.
• Mechanistic Biochemistry Research: Employed to investigate the catalytic mechanism, kinetics, and inhibition of the NQO1 enzyme in purified systems.
• Cancer Research: Facilitates studies on the role of NQO1 in cancer cell metabolism, oxidative stress response, and the evaluation of NQO1-targeted chemotherapeutic prodrugs.
• Drug Discovery & Development: Serves as a key reagent in high-throughput screening (HTS) campaigns to identify novel NQO1 inhibitors or activators for therapeutic intervention.
• Cellular Protection Studies: Used to model and understand the cytoprotective functions of NQO1 against oxidative stress and toxic quinones.
• Biomarker Development: Aids in the development of diagnostic assays that measure NQO1 activity as a potential biomarker for certain disease states.

Basic Information

Product Name	Nqo1 Substrate CAS NO 2304503-05-5
CAS No.	2304503-05-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NQO1 Substrate; NAD(P)H Dehydrogenase [Quinone] 1 Substrate; Quinone Oxidoreductase Substrate; DT-Diaphorase Substrate; Research Compound 2304503-05-5; [IUPAC Name - Contact for details]; [Common Chemical Name - Contact for details]
EINECS	Contact for details

Quality Control

Our Nqo1 Substrate is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including purity verification by HPLC and structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and assay results is provided with every shipment to support your research documentation and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under desiccated conditions. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. Handle with standard laboratory precautions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.