Description

S-3,3'-Bis((1-Naphthyl)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Bi-2,2'-Naphthol is a sophisticated chiral ligand and building block of significant interest in advanced organic synthesis and catalysis. Its value lies in its ability to induce high stereoselectivity in asymmetric transformations, a critical requirement for producing enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise control over molecular chirality.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, including hydrogenation, addition, and coupling reactions.
• As a key precursor or intermediate in the synthesis of complex, enantiomerically pure natural products and active pharmaceutical ingredients (APIs).
• In the development of novel catalytic systems for academic and industrial research focused on green chemistry and process optimization.
• For the synthesis of advanced materials with specific optical properties, such as chiral dopants for liquid crystals.
• As a resolution agent or auxiliary in the separation of enantiomers.
• In methodology development for constructing challenging C-C and C-heteroatom bonds with high stereocontrol.

Basic Information

Product Name	S-3,3'-Bis((1-Naphthyl)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Bi-2,2'-Naphthol
CAS No.	2247513-10-4
Molecular Formula	C44H38O2
Molecular Weight	598.78 g/mol
Synonyms	(S)-3,3'-Bis(1-naphthyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2,2'-naphthol; (S)-VANOL; (S)-3,3'-Bis(1-naphthyl)-H8-BINOL; S-3,3'-Di(1-naphthyl)-H8-BINOL; Octahydro-(S)-VANOL; (S)-H8-VANOL; (S)-3,3'-Di-1-naphthyl-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthol; S-Bis(1-naphthyl)-H8-BINOL
EINECS	Contact for details

Quality Control

Our production of S-3,3'-Bis((1-Naphthyl)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Bi-2,2'-Naphthol adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, to confirm enantiomeric excess and identity. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.