Description

Dadps Biotin Alykne is a specialized, high-purity chemical building block designed for advanced bioconjugation and click chemistry applications. This compound matters because it provides a critical, reactive handle for attaching biotin tags to biomolecules, enabling sensitive detection and purification in complex biological systems. It is essential for researchers and manufacturers in the fields of proteomics, drug discovery, and diagnostic assay development who require reliable, site-specific labeling reagents.

Application

• Bioconjugation Reagent: Used for the site-specific labeling of proteins, antibodies, and peptides with biotin tags for detection (e.g., with streptavidin).
• Click Chemistry: Serves as a key intermediate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create stable triazole linkages.
• Proteomics Research: Enables the enrichment and isolation of target biomolecules in pull-down assays and mass spectrometry analysis.
• Diagnostic Development: Integral for developing sensitive ELISA, lateral flow, and other immunoassay platforms.
• Drug Discovery: Used in the synthesis of biotinylated small molecules and probes for target identification and validation.
• Material Science: Functionalization of surfaces and nanomaterials for biosensor and diagnostic device fabrication.

Basic Information

Product Name	Dadps Biotin Alykne
CAS No.	2241685-22-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Biotin-DADPS-Alkyne; DADPS-Biotin-Alkyne; Biotin alkyne derivative; N-((6-((2,5-dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)carbamoyl)-5-(3-(pent-4-yn-1-yl)-1H-1,2,3-triazol-1-yl)pentanamide (possible IUPAC); Biotin-PEG4-Alkyne analog; Biotinylation reagent with alkyne handle; Click chemistry biotin reagent
EINECS	Contact for details

Quality Control

Our Dadps Biotin Alykne is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under desiccant in a low-humidity environment. Allow the product to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/LC-MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.