Description

(+)-Biotin-Peg8-Ch2Ch2Nh2 CAS NO 2183447-27-8 is a high-purity, amine-functionalized biotin-PEG conjugate designed for advanced bioconjugation and linker applications. This compound is critical for researchers and manufacturers requiring precise, stable, and hydrophilic spacers to attach biotin tags to biomolecules, surfaces, or nanoparticles. It is primarily utilized in the pharmaceutical, diagnostic, and life science research sectors for developing targeted drug delivery systems, diagnostic assays, and affinity purification platforms.

Application

• Bioconjugation Linker: Serves as a hydrophilic, flexible spacer for attaching biotin to antibodies, proteins, peptides, or oligonucleotides without compromising biological activity.
• Drug Delivery Systems: Used in the synthesis of biotinylated prodrugs or targeted nanocarriers that leverage the high-affinity streptavidin-biotin interaction for site-specific delivery.
• Diagnostic Assay Development: Essential for functionalizing surfaces (e.g., chips, beads, plates) in ELISA, lateral flow assays, and biosensors to capture target analytes.
• Affinity Purification: Enables the immobilization of biotinylated ligands on streptavidin/avidin resins for the purification of specific biomolecules.
• Cell Surface Labeling & Imaging: Facilitates the tagging of cell surface receptors or other membrane proteins for flow cytometry, microscopy, and in vivo imaging studies.
• Material Science & Nanotechnology: Used to biotinylate nanoparticles, quantum dots, or polymers to create smart materials for biomedical applications.

Basic Information

Product Name	(+)-Biotin-Peg8-Ch2Ch2Nh2
CAS No.	2183447-27-8
Molecular Formula	C41H76N4O13S
Molecular Weight	889.13 g/mol
Synonyms	Biotin-PEG8-amine; Biotin-PEG8-NH2; Biotin-PEG8-Amine; Biotinylated PEG8 amine; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]pentanamide; Biotin-PEG8-C2-NH2; (+)-Biotin-PEG8-ethylamine; PEG8-Biotin-NH2
EINECS	Contact for details

Quality Control

Our (+)-Biotin-Peg8-Ch2Ch2Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, to ensure compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant to maintain stability, as the compound is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, water, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.