Description

Fluorescein-Peg5-Acid CAS NO 2183440-40-4 is a high-purity, heterobifunctional polyethylene glycol (PEG) linker featuring a fluorescein fluorophore for detection and a carboxylic acid group for conjugation. This compound is essential for creating fluorescently labeled probes, biomolecules, and nanoparticles with precise control over spacing and solubility. It is primarily needed by researchers and manufacturers in bioconjugation, diagnostic assay development, pharmaceutical research, and advanced materials science.

Application

• Fluorescent Labeling of Biomolecules: Conjugation to antibodies, peptides, proteins, or oligonucleotides for detection and imaging applications.
• Diagnostic Reagent Synthesis: Key building block for fluorescent probes and sensors used in ELISA, flow cytometry, and lateral flow assays.
• Drug Delivery & Pharmaceutical Research: Functionalization of drug carriers, liposomes, or polymer conjugates to enable tracking and biodistribution studies.
• Biomaterials and Surface Modification: Creating fluorescently tagged surfaces or hydrogels for cell culture and tissue engineering research.
• Chemical Biology Tools: Development of activity-based probes for studying enzyme function and biomolecular interactions.
• Nanoparticle Functionalization: Attaching fluorescent PEG chains to quantum dots, gold nanoparticles, or other nanomaterials to enhance biocompatibility and enable tracking.

Basic Information

Product Name	Fluorescein-Peg5-Acid
CAS No.	2183440-40-4
Molecular Formula	C43H53NO16
Molecular Weight	839.9 g/mol
Synonyms	5(6)-Carboxyfluorescein-PEG5-acid; 5/6-FAM-PEG5-COOH; Fluorescein-PEG5-Propionic Acid; 3,6-Dihydroxy-9-[2-(carboxyethyl)-1,3-dioxo-5,8,11,14,17-pentaoxa-2-azanonadecan-19-yl]xanthen-6-ium-3-one; 5(6)-FAM-PEG5-acid; 6-FAM-PEG5-C2-acid; Fluorescein-Pentaethylene Glycol-Acid; PEG5-Fluorescein Acid Linker
EINECS	Contact for details

Quality Control

Our Fluorescein-Peg5-Acid is manufactured under strict quality protocols to ensure batch-to-batch consistency and high performance. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting research and cGMP-grade applications where required.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Orange to red solid or powder
Identification (HPLC)	Retention time matches reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95% (Area % at 254 nm / 495 nm)
Water Content (KF)	≤ 1.0 %
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.