Description

Hs-Peg7-Ch2Ch2N3 is a heterobifunctional polyethylene glycol (PEG) linker featuring a terminal azide group. This compound is engineered to facilitate controlled bioconjugation and click chemistry reactions, enabling the precise modification of biomolecules, surfaces, and polymers. It is a critical reagent for researchers and manufacturers in the fields of biopharmaceutical development, advanced material science, and diagnostic assay production.

Application

• Bioconjugation and ADC Development: Used as a linker for attaching cytotoxic drugs to antibodies in Antibody-Drug Conjugate (ADC) therapeutics.
• PEGylation of Biomolecules: Serves as a spacer to modify peptides, proteins, and oligonucleotides, improving their solubility, stability, and pharmacokinetic profiles.
• Surface Functionalization: Enables the modification of nanoparticles, quantum dots, and biosensor surfaces for targeted delivery and diagnostic applications.
• Click Chemistry Scaffold: The azide group participates in copper-catalyzed or strain-promoted azide-alkyne cycloaddition (SPAAC) for modular assembly of complex molecular architectures.
• Hydrogel and Polymer Synthesis: Acts as a cross-linking agent or functional modifier in the creation of biocompatible hydrogels and smart polymers.
• Diagnostic Reagent Preparation: Utilized in the development of fluorescent probes, imaging agents, and assay components for research and clinical diagnostics.

Basic Information

Product Name	Hs-Peg7-Ch2Ch2N3
CAS No.	2148986-06-3
Molecular Formula	C23H45N3O9
Molecular Weight	507.6 g/mol
Synonyms	Azido-PEG7-acid; 17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-oic acid; HS-PEG7-N3; Heterobifunctional PEG linker, Azide-PEG7-acid; 2-[2-[2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid; N3-PEG7-COOH; PEG7-Azide-Acid
EINECS	Contact for details

Quality Control

Our Hs-Peg7-Ch2Ch2N3 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and MS for identity verification, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its moisture-sensitive and easily oxidized nature. Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or oil
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.