Description

T-Boc-n-Amido-Peg9-Azide is a heterobifunctional polyethylene glycol (PEG) linker featuring a tert-butyloxycarbonyl (Boc)-protected amine at one terminus and an azide group at the other. This compound is essential for creating stable, water-soluble conjugates in bioconjugation and materials science, where controlled, orthogonal reactivity is required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing drug delivery systems, diagnostic probes, and functionalized surfaces.

Application

• Bioconjugation and ADC Development: Serves as a key linker for connecting antibodies, proteins, or peptides to cytotoxic drugs, fluorophores, or other payloads via click chemistry and amine coupling.
• PEGylation Reagent: Used to modify therapeutic peptides, proteins, and nanoparticles to enhance solubility, prolong circulation half-life, and reduce immunogenicity.
• Crosslinking Agent: Facilitates the formation of hydrogels and polymer networks for tissue engineering and controlled release applications.
• Surface Functionalization: Enables the modification of biosensors, microarrays, and other solid supports with bioactive molecules.
• Click Chemistry Building Block: The azide terminus readily participates in copper-catalyzed or strain-promoted azide-alkyne cycloaddition (SPAAC) reactions for modular synthesis.
• Protecting Group Strategy: The acid-labile Boc group allows for selective deprotection and sequential conjugation, enabling complex multi-step synthetic routes.

Basic Information

Product Name	T-Boc-n-Amido-Peg9-Azide
CAS No.	2112731-50-5
Molecular Formula	C34H66N4O13
Molecular Weight	738.91 g/mol
Synonyms	1-tert-Butyl 19-azido-4,7,10,13,16-pentaoxa-2-azaicosane-1,19-dioate; 2,5,8,11,14,17,20-Heptaoxadocosane-22-azide, 1-(1,1-dimethylethyl) 23-[[(1,1-dimethylethoxy)carbonyl]amino]-; Boc-NH-PEG9-N3; Boc-Amine-PEG9-Azide; tert-Butyl (19-azido-4,7,10,13,16-pentaoxa-2-azaicosan-1-yl)carbamate; Azido-PEG9-Boc-amine; Heterobifunctional PEG linker Boc-PEG9-N3
EINECS	Contact for details

Quality Control

Our T-Boc-n-Amido-Peg9-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to support your research and development, ensuring compliance with critical application requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at -20°C or below under desiccant for long-term stability. This compound is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.