Description

N,N'-Bis-(Azide-Peg3)-Chlorocyclohexenyl Cy7 is a specialized bifunctional cyanine dye derivative engineered for advanced bioconjugation and labeling applications. This compound matters for researchers and developers requiring precise, high-stability fluorescent probes with dual reactive azide groups for copper-free click chemistry. Professionals in pharmaceutical R&D, bioimaging, and diagnostic assay development need this reagent to create next-generation targeted imaging agents and therapeutic conjugates.

Application

• Bioconjugation and Probe Synthesis: Utilized as a key intermediate for attaching the near-infrared Cy7 fluorophore to biomolecules (antibodies, peptides, oligonucleotides) via strain-promoted azide-alkyne cycloaddition (SPAAC).
• In Vivo and In Vitro Imaging: Serves as a building block for developing NIR fluorescent contrast agents for deep-tissue imaging, tumor targeting, and cellular tracking.
• Diagnostic Assay Development: Enables the labeling of detection components in lateral flow assays, ELISA, and other immunoassays requiring sensitive NIR detection.
• Polymer and Material Science: Used to functionalize nanoparticles, dendrimers, and polymeric materials with fluorescent properties for tracking and characterization.
• Pharmaceutical Research: Applied in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics where a traceable fluorescent payload is required.
• Flow Cytometry and Microscopy: Facilitates the creation of custom fluorescent tags for cell surface labeling and intracellular staining applications.

Basic Information

Product Name	N,N'-Bis-(Azide-Peg3)-Chlorocyclohexenyl Cy7
CAS No.	2107273-84-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cy7-PEG3-azide dichloride derivative; Bis-azido-PEG3-Cy7 cyclohexenyl chloride; N,N'-Bis(3-azidopropyloxypropyl)-chlorocyclohexenyl Cyanine 7; Chlorocyclohexenyl-Cy7-bis-PEG3-azide; Azide-PEG3-Cy7 crosslinker; Cy7 dye with bis-azido PEG linker; Near-infrared fluorescent azide linker; SPAAC-reactive Cy7 derivative
EINECS	Contact for details

Quality Control

Our N,N'-Bis-(Azide-Peg3)-Chlorocyclohexenyl Cy7 is manufactured under strict quality protocols to ensure batch-to-batch consistency and high performance. Each lot undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	Dark green to blue solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 1.0%
Solubility	Soluble in DMSO, DMF, dichloromethane

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.