Description

n-(Ac-Peg3)-N'-(Azide-Peg3)-Cy7 Chloride is a heterobifunctional, near-infrared fluorescent dye derivative designed for advanced bioconjugation and labeling applications. This compound matters for researchers and developers requiring precise, stable, and highly sensitive labeling of biomolecules such as proteins, antibodies, and oligonucleotides. It is primarily needed by professionals in the pharmaceutical, biotechnology, and diagnostic industries for applications in bioimaging, assay development, and targeted drug delivery research.

Application

• Bioconjugation and Protein Labeling: Utilized for site-specific labeling of proteins, antibodies, and peptides via click chemistry (azide-alkyne cycloaddition) and amine-reactive (NHS ester) chemistry.
• Bioimaging and Cell Tracking: Serves as a critical reagent for in vitro and in vivo near-infrared (NIR) fluorescence imaging, offering deep tissue penetration and low background signal.
• Diagnostic Assay Development: Used in the development of sensitive fluorescence-based immunoassays, lateral flow tests, and biosensors.
• Drug Delivery Research: Enables the labeling and tracking of drug carriers, nanoparticles, and antibody-drug conjugates (ADCs) to study their biodistribution and pharmacokinetics.
• Nucleic Acid Labeling: Applicable for labeling oligonucleotides and other nucleic acid probes for fluorescence in situ hybridization (FISH) and real-time PCR applications.
• Material Science and Surface Modification: Used to functionalize surfaces, polymers, and nanomaterials with fluorescent properties for sensor and device fabrication.

Basic Information

Product Name	n-(Ac-Peg3)-N'-(Azide-Peg3)-Cy7 Chloride
CAS No.	2107273-00-5
Molecular Formula	C58H84ClN5O12
Molecular Weight	1050.76 g/mol
Synonyms	Cy7-PEG3-Azide-PEG3-NHS ester; Cy7 NHS ester-PEG3-Azide-PEG3-Acetate; 1-(2,5-Dioxopyrrolidin-1-yl) 24-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)-24-oxo-3,6,9,12,15,18,21-heptaoxatetracosan-1-oate Cy7 chloride; N-(Acetyl-PEG3)-N'-(Azido-PEG3)-Cyanine7 chloride; Cy7-PEG3-N3-PEG3-NHS; Azide-PEG3-Cy7-PEG3-NHS ester; Sulfo-Cy7 NHS ester-PEG3-Azide-PEG3-Acetate analog (non-sulfonated)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of n-(Ac-Peg3)-N'-(Azide-Peg3)-Cy7 Chloride is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and functional integrity. Certificates of Analysis (COA) with detailed specifications are available upon request. We adhere to a quality management system to ensure traceability and batch-to-batch consistency suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Dark green to blue solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Functional Group Integrity (NMR)	Confirms presence of NHS ester and azide groups
Extinction Coefficient	≥ 200,000 cm-1M-1 at ~750 nm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.