Description

4,7,10-Trioxa-13-Azahexadecanoic Acid, 16-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)-14-Oxo- is a specialized heterocyclic carboxylic acid derivative featuring a maleimide functional group. This compound matters for its role as a versatile bifunctional linker in advanced material science and bioconjugation chemistry. It is primarily needed by R&D and production teams in the pharmaceutical, biotech, and polymer industries for creating functionalized surfaces, drug delivery systems, and cross-linked polymer networks.

Application

• Bioconjugation Reagent: Used for the covalent attachment of peptides, proteins, or other biomolecules to surfaces or carrier molecules via the reactive maleimide group.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to introduce carboxylic acid and maleimide functionalities into polymer backbones for enhanced properties.
• Surface Functionalization: Applied to modify material surfaces (e.g., gold, silica) to create reactive sites for subsequent immobilization of ligands or catalysts.
• Drug-Linker Intermediate: A key synthetic intermediate in the development of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Hydrogel Formation: Utilized in the synthesis of smart hydrogels and biomaterials that respond to specific stimuli, leveraging its cross-linking capability.
• Diagnostic Assay Development: Employed in the fabrication of biosensors and diagnostic devices by linking recognition elements to transducers.

Basic Information

Product Name	4,7,10-Trioxa-13-Azahexadecanoic Acid, 16-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)-14-Oxo-
CAS No.	2055353-75-6
Molecular Formula	C17H26N2O8
Molecular Weight	398.40 g/mol
Synonyms	16-Maleimido-4,7,10-trioxa-13-azahexadecanoic acid; 16-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,7,10-trioxa-13-azahexadecanoic acid; Maleimide-PEG3-COOH; Maleimide-PEG3-acid; 1-[11-Carboxy-3,6,9-trioxa-10-azaundecyl]maleimide; Maleimido-PEG3-propionic acid; Amine-PEG3-Maleimide carboxylic acid; MAL-PEG3-COOH
EINECS	Contact for details

Quality Control

Our production of 4,7,10-Trioxa-13-Azahexadecanoic Acid, 16-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)-14-Oxo- adheres to stringent quality protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and hydrolysis. Allow the container to reach room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.