Description

(+)-Biotin-Peg6-Nhs Ester is a high-purity, heterobifunctional crosslinking reagent designed for precise bioconjugation. This compound is critical for researchers and manufacturers who require stable, site-specific labeling of biomolecules with biotin for detection, purification, or targeting applications. It is primarily utilized in the development of advanced diagnostics, targeted therapeutics, and sophisticated biochemical research tools within the pharmaceutical, biotechnology, and life sciences sectors.

Application

• Antibody-Drug Conjugate (ADC) Development: Site-specific conjugation of cytotoxic payloads or imaging agents to monoclonal antibodies.
• Diagnostic Assay Reagent: Biotinylation of proteins, peptides, or oligonucleotides for use in ELISA, lateral flow assays, and other immunoassay platforms.
• Affinity Purification Probes: Creation of biotin-tagged ligands for capture on streptavidin/avidin resins.
• Cell Surface Labeling: Modification of cell surface proteins or carbohydrates for flow cytometry or microscopy studies.
• Protein-Protein Interaction Studies: Crosslinking agents for studying biomolecular interactions and complex formation.
• Nanoparticle Functionalization: Conjugation of targeting ligands (e.g., antibodies, peptides) to nanoparticles for drug delivery or imaging.
• Biosensor Development: Immobilization of biorecognition elements onto sensor surfaces.
• Next-Generation Sequencing (NGS): Preparation of biotinylated adapters or probes for library preparation and target enrichment.

Basic Information

Product Name	(+)-Biotin-Peg6-Nhs Ester
CAS No.	2055045-04-8
Molecular Formula	C33H56N4O13S
Molecular Weight	748.88 g/mol
Synonyms	Biotin-PEG6-NHS Ester; Biotinamidohexanoic acid-PEG6-NHS ester; Biotin-(PEG)6-NHS; Biotin-PEG6-NHS; Biotinamidocaproyl-PEG6-NHS ester; Biotinamidocaproyl-PEG6-NHS ester; Biotin-PEG6-NHS; Biotin-PEG6-NHS Ester; Biotin-PEG6-N-hydroxysuccinimide ester; Biotin-PEG6-N-hydroxysuccinimide ester
EINECS	Contact for details

Quality Control

Our (+)-Biotin-Peg6-Nhs Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment, NMR and MS for structural confirmation, and functional testing to ensure optimal conjugation efficiency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability, consistency, and compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.