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T-Boc-Aminooxy-Peg7-Methane CAS NO 2055041-27-3


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CAS No.:2055041-27-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

T-Boc-Aminooxy-Peg7-Methane is a high-purity, heterobifunctional polyethylene glycol (PEG) linker featuring a tert-butoxycarbonyl (Boc)-protected aminooxy group and a methanolic terminus. This compound is specifically engineered for the site-specific conjugation of biomolecules, such as proteins and peptides, through oxime ligation, offering superior control and stability. It is an essential reagent for researchers and developers in the fields of bioconjugation, antibody-drug conjugate (ADC) development, and advanced pharmaceutical formulation. The product is supplied under stringent quality control to ensure batch-to-bay consistency for critical R&D and manufacturing processes.

Application

  • Bioconjugation reagent for site-specific modification of proteins, antibodies, and peptides.
  • Key building block in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics.
  • Functional linker for surface modification and functionalization of nanoparticles and drug delivery systems.
  • Tool compound for PEGylation strategies to improve pharmacokinetic properties of biologics.
  • Intermediate in the synthesis of complex molecular probes and diagnostic agents.
  • Crosslinking agent for hydrogel formation and biomaterial engineering.
  • Research tool in chemical biology for studying protein interactions and functions.

Basic Information

Product Name T-Boc-Aminooxy-Peg7-Methane
CAS No. 2055041-27-3
Molecular Formula C31H63NO15
Molecular Weight 689.83 g/mol
Synonyms 1-Aminooxy-2,5,8,11,14,17,20-heptaoxadocosan-22-ol, 1-(1,1-Dimethylethoxy)carbonyl ester; tert-Butyl (22-hydroxy-3,6,9,12,15,18,21-heptaoxa-2-azadocosyl) carbamate; Boc-NH-O-PEG7-OH; Boc-Aminooxy-PEG7-alcohol; Aminooxy-PEG7-t-butyl ester; Heterobifunctional PEG linker, Boc-aminooxy-PEG7-methanol; T-Boc-NH-O-(CH2CH2O)7-CH2OH
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Quality Control

Our T-Boc-Aminooxy-Peg7-Methane is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for pharmaceutical research and development. Each batch is characterized by NMR, HPLC, and mass spectrometry to confirm identity, purity, and absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white solid or viscous liquid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Molecular Weight Confirmation (MS) Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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