Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl n-Me-D-Gln(Trt)-Oh is a sophisticated, protected amino acid derivative designed for advanced peptide synthesis. This compound matters for its role as a critical building block in the production of complex, non-natural peptides and peptidomimetics, enabling precise control over stereochemistry and side-chain functionality. Pharmaceutical researchers and fine chemical manufacturers need it for developing novel therapeutic candidates, particularly in areas requiring high-purity, custom peptide sequences.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of N-methyl-D-glutamine analogs into peptide chains.
• Peptidomimetic Drug Discovery: Used in research to create metabolically stable peptide analogs with enhanced bioavailability and receptor selectivity.
• Combinatorial Chemistry Libraries: Serves as a specialized monomer for generating diverse libraries of peptide-based compounds for high-throughput screening.
• API Intermediate Production: Employed in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) where specific glutamine derivatives are required.
• Bioconjugation and Probe Development: Useful for creating labeled peptides or peptide-based probes for diagnostic and research applications.
• Academic and Industrial R&D: A valuable reagent for studying peptide structure-activity relationships and developing new synthetic methodologies.

Basic Information

Item	Details
Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl n-Me-D-Gln(Trt)-Oh
CAS No.	2044710-89-4
Molecular Formula	C46H42N2O5
Molecular Weight	702.85 g/mol
Synonyms	Fmoc-N-Me-D-Gln(Trt)-OH; N-α-Fmoc-N-γ-trityl-N-methyl-D-glutamine; Fmoc-N-methyl-D-glutamine(trityl)-OH; Fmoc-N-Me-D-Glutamine(Trt)-OH; (9-Fluorenylmethoxycarbonyl)-N-methyl-D-glutamine trityl ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-glutamine N'-trityl; Protected N-methyl-D-glutamine derivative; Fmoc-D-N-Me-Gln(Trt)-OH
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl n-Me-D-Gln(Trt)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.