Description

19-Noretiocholanolone Glucuronide is a high-purity conjugated metabolite of the steroid hormone etiocholanolone, specifically designed for research and diagnostic applications. This compound serves as a critical reference standard and calibrator in analytical chemistry, ensuring accurate quantification and method validation. It is primarily utilized by pharmaceutical R&D laboratories, clinical diagnostic manufacturers, and academic institutions engaged in endocrinology and metabolomics studies.

Application

• Reference Standard for LC-MS/MS: Primary application as a certified internal standard or calibrator for the precise quantification of steroid metabolites in complex biological matrices like serum, urine, and tissue samples.
• Clinical Diagnostics Development: Essential component in the development and validation of immunoassays and mass spectrometry-based diagnostic kits for hormonal disorders and metabolic profiling.
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetic (DMPK) studies to investigate the glucuronidation pathways of steroid-based pharmaceuticals.
• Endocrinology & Metabolomics: A key analyte in research focused on androgen metabolism, steroid profiling, and the discovery of biomarkers for related diseases.
• Quality Control (QC) Material: Serves as a high-quality control sample in laboratory proficiency testing and to ensure the consistency and accuracy of analytical instruments.

Basic Information

Product Name	19-Noretiocholanolone Glucuronide
CAS No.	294213-87-9
Molecular Formula	C25H36O9
Molecular Weight	480.55 g/mol
Synonyms	19-Nor-5β-Androstane-3α,17β-diol-17-Glucuronide; 3α,17β-Dihydroxy-5β-estran-17-yl β-D-Glucopyranosiduronic Acid; Etiocholanolone-17-Glucuronide (19-Nor); 19-Nor-5β-Androstane-3α,17β-diol 17-Glucuronide; 19-Noretiocholanolone 17-Glucuronide; 5β-Estrane-3α,17β-diol 17-Glucuronide; 17β-Hydroxy-5β-estran-3α-yl β-D-Glucopyranosiduronic Acid
EINECS	Contact for details

Quality Control

Our 19-Noretiocholanolone Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and diagnostic use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.